Luke returned to Houston from KC June 5. The doctors at Children’s Mercy Hospital in
KC monitored him for four weeks after infusion of the CART cells. They took labs 2-3 times a week.
At the
four week point they took a bone marrow sample and drew spinal fluid.
KC did a flow cytometery on the bone marrow. The flow cytometry picked up no leukemia cells
and the pathologist saw nothing suspicious in the biopsy. The bone marrow sample was sent to Children’s
Hospital of Philadelphia for additional lab testing required for the clinical
trial. The results from CHOP came back today and
confirmed there was no leukemia!!.
Luke’s other labs were good. Noting bad showed up in his blood or spinal
fluid. Kidney function was good. Liver results were not perfect but nothing
the doctors were concerned with.
Luke was thrilled to finally have his PICC line removed and
become tube free. He’s actually has put
on weight and admitted he might need to do a few sit-ups. He is hopeful of returning to school in the
fall.
What’s left is to wait and see. For the next three months Luke is scheduled
to return to KC for labs as part the monitoring requirements of the clinical
trial. The doctors will be watching for
B-cells in his blood/bone marrow as that a sign the CART-cells are no longer
active and the cancer has returned.
Knowing that the CART-cells are multiplying and killing the
leukemic B-cells is truly great news.
The initial results from the clinical trial
are encouraging but the study doctors let you know the first patient was
treated only 2.5 years ago and no one knows what to expect long term. Hopefully the “asshat” is dead, long live the
CART-cells!
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